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FDA

The raw, unprocessed horse-chestnut seeds can be toxic. Avoid ingestion. Horse-chestnut uses during pregnancy and lactation has not been fully validated, especially in the first trimester. Use only under professional supervision. Avoid internal use in children. Avoid internal use in patients with kidney or liver disease. Do not apply gels, ointments, or lotions on ulcerated or broken skin. In rare cases, side effects such as nausea, gastric upset and rash may occur. Since horse-chestnut contains active principles that may interfere with normal blood clotting, patients with bleeding disorders or those taking aspirin or warfarin should consult a health care professional before taking this herb. Discontinue internal use of this herb at least one week before surgery.